Financial Support/Grants
Historically, the Department of Otolaryngology has enjoyed relatively high levels of outside funding. Grants to various faculty members within the department and the most current, ongoing projects are listed below.
WSU medical resident wins grant to explore salivary method for diagnosing common esophageal disease
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2019
Ho-Sheng Lin, M.D., Site PI, (J Zhang, main PI) Department of Defense/CDMRP, "Clinical Trial of Etanercept (TNF-alpha Blocker) for Treatment of Blast-Induced Tinnitus" 9/30/2018-09/29/2022 $355,434.
Drescher, D.G., Ph.D., PI, Drescher, M.J., Ph.D., Co-PI, “Molecular-Functional Comparison of the Dysferlin Membrane Repair Complex with the Otoferlin Synaptic Complex,” Jain Foundation, 6/1/19-5/31/20 $106,864
Jinsheng Zhang, Ph.D. Co-PI, (Altschuler, PI) Department of Defense, "Mechanism Based Prevention of Noise-Induced Tinnitus: Protection and Repair of Peripheral Auditory Neuropathy" 09/30/2017-09/29/2020, $1,507,849Zhengqing Hu, Ph.D., PI, “Developing novel stem cell-based epigenetic approaches to treat hearing loss” Veterans Affairs Merit Review (Parent I01), 10/2018-09/2022, $1,100,000
Zhengqing Hu, Ph.D., PI, “Regeneration of auditory synaptic contacts using stem cell based approaches” NIH/NIDCD (Parent R01), 05/2014-04/2020, $1,062,500
Jinsheng Zhang, Ph.D., PI. Department of Defense/CDMRP, "Clinical Trial of Etanercept (TNF-alpha Blocker) for Treatment of Blast-Induced Tinnitus" 9/30/2018-09/29/2022 $8,651,782
Jinsheng Zhang, Ph.D. PI. Department of Defense/CDMRP, "Targeting TNF-Alpha for Treatment of Blast-Induced Tinnitus" 09/30/2015-09/29/2019 $1,499,107
Hao Luo, Ph.D.,PI “Cochlear electrical stimulation induced tinnitus suppression and related neural activity change in the rat’s inferior colliculus.” Hearing Health Foundation, 07/01/2019-06/30/2020, $29,959 -
2018
Zhengqing Hu - PI. Veterans Affairs Merit Review (Parent I01) (I01 RX0021000) "Developing novel stem cell-based epigenetic approaches to treat hearing loss" 12/2017-11/2021 $1,100,000
Dennis G. Drescher, PI, Marian J Drescher, Co-PI, "Molecular-Functional Comparison of the Dysferlin Membrane Repair Complex with the Otoferlin Synaptic Complex," Jain Foundation, 10/1/17-3/31/19 Funded $117,384
Jinsheng Zhang, Ph.D. Co-PI, (Altschuler, Holt, PIs) Department of Defense, "Mechanism Based Prevention of Noise-Induced Tinnitus: Protection and Repair of Peripheral Auditory Neuropathy" 09/30/2017-09/29/2020, $1,507,849
Zhengqing Hu - PI. NIDCD/NIH (1R01DC013275) "Regeneration of auditory synaptic contacts using stem cell based approaches" 05/2014-04/2019, $1,062,500
Jinsheng Zhang, Ph.D. PI. Department of Defense/CDMRP, "Targeting TNF-Alpha for Treatment of Blast-Induced Tinnitus" 09/30/2015-09/29/2019 $1,499,107
Jinsheng Zhang, Ph.D. Co-PI, (Bao, PI). Department of Defense/CDMRP, "Developing TNF-Alpha-Mediated Treatment for Blast-Induced Tinnitus" 01/15/2015-01/14/2019 $1,496,233 -
2017
Drescher, D.G., PI, Drescher, M.J., Co-PI, "Molecular-Functional Comparison of the Dysferlin Membrane Repair Complex with the Otoferlin Synaptic Complex," Jain Foundation, 10/1/17-9/30/18 117,384
Jinsheng Zhang, Ph.D. Co-PI, (Altschuler, PI) Departmentof Defense, "Mechanism Based Prevention of Noise-Induced Tinnitus: Protection and Repair of Peripheral Auditory Neuropathy" 09/30/2017-09/29/2020, $1,507,849
Zhengqing Hu - PI. NIDCD/NIH (1R01DC013275) "Regeneration of auditory synaptic contacts using stem cell based approaches" 05/2014-04/2019, $1,062,500
Zhengqing Hu - PI. Veterans Affairs Merit Review (Parent I01) (I01 RX0021000) "Developing novel stem cell-based epigenetic approaches to treat hearing loss" 12/2017-11/2021 $1,100,000
Jinsheng Zhang, Ph.D. PI. Martha Entenmann Tinnitus Research Center, Inc. "Assess the calpain inhibitory Gabadur as a potential therapy for noise-induced subjective tinnitus of the severe disabling type”. 04/01/2015-03/31/2018 $180,000
Zhengqing Hu - PI. Wayne State University Grants Plus Grant "Generation of functional human hair cells from inner ear progenitors via genome-wide demethylation" 03/2015-11/2017 $100,000 -
2016
Drescher, D.G., PI, Drescher, M.J., Co-PI, "Molecular-Functional Comparison of the Dysferlin Membrane Repair Complex with the Otoferlin Synaptic Complex," Jain Foundation, 2016-2017 $119,734
Jinsheng Zhang, Ph.D. PI. Martha Entenmann Tinnitus Research Center, Inc. "Assess the calpain inhibitory Gabadur as a potential therapy for noise-induced subjective tinnitus of the severe disabling type”. 04/01/2015-03/31/2018 $180,000
Jinsheng Zhang, Ph.D. PI, Department of Defense, "Targeting TNF-Alpha for Treatment of Blast-Induced Tinnitus" Grant ID: PR141168, 7/2015-6/2018, $1,499,107
Jinsheng Zhang, Ph.D. Co-I (Bao, PI), Department of Defense, "Developing TNF-Alpha-Mediated Treatment for Blast-Induced Tinnitus" Grant ID: MR130317, 1/2015-1/2018, $1,496,233
Zhengqing Hu - PI. Wayne State University Grants Plus Grant "Generation of functional human hair cells from inner ear progenitors via genome-wide demethylation" 03/2015-11/2017 $100,000 -
2015
Zhengqing Hu - PI. Wayne State University Grants Plus Grant "Generation of functional human hair cells from inner ear progenitors via genome-wide demethylation" 03/2015-11/2017 $100,000
Drescher, D.G., PI, Drescher, M.J., Co-PI, R01, "Identification of Acoustico-Lateralis Transmitters," National Institutes of Health, $1,881,250 (2015: 33rd year)
Drescher, D.G., PI, Drescher, M.J., Co-PI, "Molecular-Functional Comparison of the Dysferlin Membrane Repair Complex with the Otoferlin Synaptic Complex," Jain Foundation, 2015-2016 $121,764
Jinsheng Zhang, Ph.D. PI, Department of Defense, "Targeting TNF-Alpha for Treatment of Blast-Induced Tinnitus" Grant ID: PR141168, 7/2015-6/2018, $1,499,107
Jinsheng Zhang, Ph.D. PI, NIH/NIDCD, "Cochlear Electrical Stimulation to Suppress Tinnitus in Rats" Grant ID: R21 DC014335-01 1/2015-12/2016, $420,657
Jinsheng Zhang, Ph.D. Co-I (Bao, PI), Department of Defense, "Developing TNF-Alpha-Mediated Treatment for Blast-Induced Tinnitus" Grant ID: MR130317, 1/2015-1/2018, $1,496,233
Jinsheng Zhang, Ph.D. PI, Martha Entenmann Tinnitus Research Center Inc, "Assess the calpain inhibitory Gabadur as a potential therapy for noise-induced subjective tinnitus of the severe disabling type". 4/205-3/208, $180,000
George Yoo, M.D. Co-I (Gregory Wolf, M.D.-PI) NCI NIH, 5P50 CA 097248-7, 10% "SPORE and Head and Neck Cancer; The Molecular Basis of Head and Neck Cancer Biology Treatment and Prevention" 1/2009-12/2015 -
2014
Zhenqing Hu, MD, PhD, PI, NIDCD/NIH (1 R01 DC013275) "Regeneration of auditory synaptic contacts using stem cell based approaches" $1,615,000.
Ho-Sheng Lin, M.D. "Office of the Vice President for Research, Bridge Funding, PI, "Identification of Early Marker for Head and Neck Cancer through Antibody Profiling" $35,000.
Mahdi Shkoukani, M.D. AAFPRS Leslie Bernstein Resident Research Grant, Faculty Advisor & Co-PI "Biomechanics of the Orbital Floor Fracture" $5000. 2014George H. Yoo, M.D. NCI NIH, 5P50 CA 097248-7, 10% "SPORE and Head and Neck Cancer; The Molecular Basis of Head and Neck Cancer Biology Treatment and Prevention" CI: G Yoo, (PI: Gregory Wolf, MD) Provide scientific direction and coordination for the implementation and quality control of the study. 1/1/09-12/31/15
George H. Yoo, M.D. NCI-Southwest Oncology Group, Wayne State University institutional grant. U10 CA14028 20-10%, CI: G Yoo, (PI: Lawrence Flaherty, M.D.) Provide leadership of the administrative and scientific functions of SWOG. 1/2004-12/2014
Drescher, D.G., PI, Drescher, M.J., Co-PI, "Molecular-Functional Comparison of the Dysferlin Membrane Repair Complex with the Otoferlin Synaptic Complex," Jain Foundation, 2014. $121,764
Drescher, D.G., Research Stimulation Award, Office of the Vice President for Research, Wayne State University, 2014. $36,000
Drescher, D.G., Research Stimulation Award, Research and Graduate Programs, Wayne State University School of Medicine, 2014. $36,000
Drescher, D.G., Research Award, Department of Otolaryngology, Wayne State University School of Medicine, 2014. $4,500
Drescher, D.G., Research Stimulation Award, Office of the Vice President for Research, Wayne State University, 2013-2014. $52,000
JInsheng Zhang, Ph.D. (Co-PI), Dr. Yong Xu (PI), National Science Foundation. "A novel 3-dimensional neural probe technology combining electrical and chemical interfaces" Grant ID: ECCS-1028564, 10/2010-09/2014, $330,000
Jinsheng Zhang, Ph.D. PI, Tinnitus Research Consortium. "Role of the amygdala and its interactions with auditory structures in tinnitus" 07/2010-06/2014, $297,202
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2013
Zhenqing Hu, MD, PhD, PI, The Carls Endowment Trust, "Regeneration of auditory synapses for the treatment of hearing loss in children" $40,000.
Zhenqing Hu, MD, PhD, Co-PI, Wayne State University Grants Plus "A flexible cochlear implant for high-resolution functional stimulation and for tissue regeneration" (PI: Cheng, Engineering) $100,000.
Ho-Sheng Lin, M.D. Office of the Vice President for Research, Bridge Funding, PI, "Identification of Early Marker for Head and Neck Cancer through Antibody Profiling" $35,000.
Ho-Sheng Lin, M.D. Biomedical Laboratory Research & Development service of the VA Office of Research and Development, PI. "Proteomic Approach for Early Detection of Head and Neck Cancer" $500,000.Robert S. Hong, MD, PhD, Sonitus Medical Inc., Site Investigator "Evaluation of benefit for treatment of single sided deafness (SSD) between two bone conduction prosthetic devices: osseointegrated implant versus maxilla anchored removable oral appliance ("SoundBite")- Multi-center clinical trial.
Michael Carron, M.D. and Giancarlo Zuliani, M.D. Co-Investigators. "Use of Cynaoacrylate to Salvage Endotines in Endoscopic Browlifting." Microaire Corporation. $3500.00
Giancarlo Zuliani, Co-I, "Use of Cyanoacrylate for Improved Stability in Endoscopic Brow Lifting." MicroAire, 2013, $5000.
Edwin M. Monsell, M.D., Ph.D., P-I, extension of Active Hearing Loss in Paget's Disease of Bone, Source of Funds: The Paget Foundation, end date 6-30-12, 1 year extension to support data analysis and preparation for publication. (no salary support) 2012-2013
Drescher, D.G., Research Stimulation Award, Research and Graduate Programs, Wayne State University School of Medicine, 2013. $20,000
Drescher, D.G., Research Stimulation Award, Office of the Vice President for Research, Wayne State University, 2013-2014. $52,000
Jinsheng Zhang, Ph.D. Co-Investigator (Project Leader), Dr. Mark Haacke (PI), WSU Enhancement Award. Center for Traumatic Brain Injury Research (CTBIR), 09/01/2010-08/31/2013, $900,000
Jinsheng Zhang, Ph.D. PI, TRI (Tinnitus Research Initiative), Germany. "Treating Tinnitus with Electro-Acupuncture (clinical trial)" 07/2010-06/2013, $31,414
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2012
Zhenqing Hu, MD, PhD, PI, Wayne State University Grants Plus "Generation of inner ear hair cell progenitors via epithelial-to-mesenchymal transition" $100,000.
Edwin M. Monsell, M.D., Ph.D., P-I, Active Hearing Loss in Paget's Disease of Bone, The Paget Foundation, $10,000. 1995-2012
Drescher, M.J., PI, Drescher, D.G., Co-PI, R01, "Adenylyl Cyclase Signaling in Ear Sensory Epithelia," National Institutes of Health, 5/2005-4/2012. $1,500,000
Jinsheng Zhang, Ph.D. PI, National Institute of Health (NIH)/ National Institute on Deafness and Other Communication Disorders (NIDCD). "Cortical electrical suppression of noise-induced tinnitus" Grant ID: 1R21 DC010059-01, 02/2009-1/2012, $418,000
Jinsheng Zhang, Ph.D. PI, National Institute of Health (NIH)/ National Institute on Deafness and Other Communication Disorders (NIDCD)." Cortical electrical suppression of noise-induced tinnitus (Supplements for purchasing Equipment)". Grant ID: 3R21 DC010059-01S1, 06/2009-01/2012, $83,245
Jinsheng Zhang, Ph.D. (Co-PI), Dr. Sean Wu (PI), President's Research Enhancement Program in Physical Sciences (WSU). "Tinnitus Diagnosis and Treatment via Innovative Acoustic/Neural Stimulus and Imaging Technologies" 06/2011-12/2012, $100,000
Jinsheng Zhang, Ph.D. Mentor/Sponsor (Jessica Ouyang, Ph.D. student, P.I.). American Association of Nurse Anesthetists Foundation (AANA). "Impact of isoflurance and sevoflurance on cortical activity: in vivo multi-channel electrophysiology studies and implications in monitoring consciousness" 01/2010-12/2012, $10,000
Edwin Monsell, M.D., Ph.D. P-I, extension of Active Hearing Loss in Paget's Disease of Bone, Source of Funds: The Paget Foundation, end date 6-30-12, 2012-2013 1-year extension to support data analysis and preparation for publication. (no salary support) -
2011
Jinsheng Zhang, Ph.D. PI, Department of Defense. "Parallel human and animal models of blast- and concussion-induced tinnitus and related traumatic brain injury (TBI)" Grant ID: W81XWH-11-2-0031, 01/2011-02/2015 $1,520,000
Ho-Sheng Lin, M.D. National Cancer Institute Phase 1 IMAT SBIR, PA08-050, 1 R43 CA139806-01. Co-PIs: Nada Khattar and Ho-Sheng Lin "Autoantibody Profiling for Serological Detection of Head and Neck Cancer" $206,140Zhenqing Hu, MD, PhD, PI, The Deafness Research Foundation Year 2 Research Grant "Innervation of in vitro-produced hair cell by neural progenitor-derived neurons" $22,500
Zhenqing Hu, MD, PhD, PI, The American Hearing Research Foundation Research Grant "Regeneration of the central processes of spiral ganglion neurons using a cell-based replacement" $20,000
Giancarlo Zuliani, M.D. Ethicon surgical grant for Wayne State University Facial Plastics Course, $1000.
Robert S. Hong, MD, PhD, Cochlear Americas, PI, "Cochlear implantation for single-sided deafness- feasibility study" $13,718
Robert S. Hong, MD, PhD, Michigan Ear Institute. PI "Endolymphatic sac decompression with intra-sac steroids"
Giancarlo Zuliani,M.D., Ethicon surgical grant for Wayne State University Facial Plastics Course, 2011, $1000.
Ramakrishnan, N.A., PI, Drescher, D.G., Co-PI, "Molecular biology and protein-protein interactions in auditory/vestibular afferent synaptic transmission" Deafness Research Foundation 2011 $25,000.
Drescher, D.G., PI, "Research Equipment Maintenance Match", Wayne State University School of Medicine, $2,000. 10/11
Drescher, D.G., PI, Drescher, M.J., Co-PI, R01, ARRA Administrative Supplement, "Identification of Acoustico-Lateralis Transmitters," National Institutes of Health, $106,250. 6/09-5/11
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2010
Ho-Sheng Lin, M.D. Biomedical Laboratory Research & Development, Service of the VA Office of Research and Development, (BLR&D) MERIT REVIEW AWARD (PARENT I01), I01 BX007080, PI "Proteomic Approach for Early Detection of Head and Neck Cancer" $500,000
Zhenqing Hu, MD, PhD, PI, The Deafness Research Foundation Year 1 Research Grant "Innervation of In Vitro-produced Hair Cell by Neural Progenitor-derived Glutamatergic Neurons" $22,500
Zhenqing Hu, MD, PhD. American Academy of Audioloy, "Implantation of Inner Ear-Derived Neural Stem Cells into the Adult Inner Ear", $10,000.
Michael Carron, MD, Giancarlo Zuliani, MD, KLS Martin, "Biomechanical analysis of Absorbable Plate and Screw Fixation of fractures with the Sonic Weld system", $4,500.
Jinsheng Zhang, PhD, Tinnitus Research Consortium, "Role of the amygdala and its interactions with auditory structures in tinnitus", $297,202.
Jinshang Zhang, PhD, Tinnitus Research Initiative, "Treating Tinitus with Electro-Acupuncture (clinical trial)", $31,414
George Yoo, MD, NCI-Southwest Oncology Group (C-I). NCI cooperative group grant 10%, 1/2006-12/2010.
Giancarlo Zuliani, M.D. KLS Martin, Co-I "Biomechanical analysis of Absorbable Plate and Screw Fixation of fractures with the Sonic Weld system". $4,300.00
Kelvin Kwong, M.D., Lions Hearing Center of Michigan, "Incidence of Otitis Media and Sensorineural Hearing Loss in Preterm Infants", $2,000.
Javan Nation, M.D., Lions Hearing Center of Michigan, "The Effect of Electrical Stimulatino of the Dorsal Cochlear Nucleus on Hearing in Periphally Deafened Animals", $2,000
Gregory Kruper, M.D., Lions Hearing Center of Michigan, "Adenoid tissue as a biofilm reservoir in the pathogenesis of chronic rhinosinusitis in children", $2,000.
Jinsheng Zhang, Ph.D. Co-Mentor/Sponsor (Na Zhu, PhD. candidate, P.I.). American Tinnitus Association (ATA). "Development of an innovative, 3D computer aided diagnosis system for tinnitus." 01/2011-12/2011 $10,000
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2009
Dennis Drescher, Ph.D., Marian Drescher, Ph.D.-NIH, "Identification of Acoustico-Lateralis Transmitters", $1,500,000.
Dennis Drescher, Ph.D.,ARRA supplement, "Identification of Acoustico-Lateralis Transmitters", 7-1-09 to 6-30-11, $161,500.
Ho-Sheng Lin, M.D., VA Merit Review/BLR&D Merit Review Award (Parent I01), "Proteomic Approach for Early Detection of Head and Neck Cancer", $200,000.
Ho-Sheng Lin, M.D., National Cancer Institute, "Serum and Salivary Immunodiagnostic in Head and Neck Cancer", $150,000.
Ho-Sheng Lin, M.D. National Cancer Institute, IMAT SBIR, PA08-050, 1 R43 CA139806-01, Co-PIs Nada Khattar and Ho-Sheng Lin. "Autoantibody Profiling for Serological Detection of Head and Neck Cancer" $206,140
Jinsheng Zhang, Ph.D., NIH/NIDCD, "Cortical electrical suppression of noise-induced tinnitus", $413,875.
Kelvin Kwong, M.D., American Tinnitus Association, "Mechanisms Underlying Acoustic Masking of Tinnitus", $10,000.
George Yoo, M.D., NCI-Southwest Oncology Group (C-I), Provide Surgical leadership of the administrative and scientific functions of SWOG, 1/2004 - 12/2009, $38,881.
James Kaltenbach, Ph.D., Paul Finlayson,Ph.D., NIDCD (R01), "Central Auditory plasticity as a basis of tinnitus", $62,354.
Paul Finlayson,Ph.D., American Tinnitus Association, "Noise-induced tinnitus: DCN hyperactivity and the cyclic-AMP pathway: Biophysical Properties. $49,954.
Jinsheng Zhang, PhD, NIH/NIDCD, "Cortical Electrical Suppression of Noise-Induced Tinnitus (EQ Equipment supplements)", $83,245.
Jessica Quyang (PhD student), Jinsheng Zhang (Sponsor), The American Association of Nurse Anethestists Foundation, "Impact of isoflurance and sevoflurance on cortical activity: in vivo multi-channel electrophysiology studies and implications in monitoring consciousness, $10,000.
Edwin Monsell, M.D., Ph.D., P-I, The Paget Foundation "Active Hearing Loss in Paget's Disease of Bone" 1995-2012 $10,000