Position Title

Professor and Chairman
Clinical Educator track, full time

Office Address

Dept. of Otolaryngology-HNS
4201 St. Antoine, 5E-UHC
Detroit, MI  48201

UPG Southfield 
26400 W. 12 Mile, Suite 111
Southfield, MI  48034
248-357-4151 

Platinum Medical Center
5250 Auto Club Dr., Ste 290A
Dearborn, MI 48126
(313) 448-9220

Troy Campus 
1560 E. Maple Road, Suite 200 
Troy, MI  48083
248-581-5200 

Wertz Clinical Cancer Center 
4100 John R 
Detroit, MI  48201
800-527-6266 

John D. Dingell VA Medical Center 
ENT Clinic, 2nd floor 
Detroit, MI  48201
313-576-1000,  64022 

Links of Interest

• Robotic Thyroidectomy
• Robotic base of tongue resection for sleep apnea
• Sleep apnea patient testimonial
• Interview - thyroid surgery with no neck scar
• Sleep apnea surgery
• Sleep apnea article
• Appointment to Chair of Department of Otolaryngology
  

Narrative Bio

Ho-Sheng Lin, MD, FACS is a Professor and the Chairman of the Department of Otolaryngology - Head and Neck Surgery at Wayne State University (WSU) School of Medicine.  He received his MD from Yale University School of Medicine and then went on to complete an Otolaryngology residency at The New York Hospital-Cornell Medical Center and New York University Medical Center. After his residency, Dr. Lin completed fellowship training in Head and Neck Surgical Oncology at Stanford University.  He joined the Department of Otolaryngology at WSU in 2002. 

Dr. Lin's clinical interests include surgical treatment of cancer and disease involving the mouth, throat, neck, thyroid, parathyroid, and salivary glands as well as surgical treatment of obstructive sleep apnea (OSA) and snoring.  He has special interest in the use of new and minimally invasive technology in head and neck surgery.  He has used Harmonic technology for minimally invasive thyroid surgery.  He is the first surgeon in the state of Michigan to use the robotic technology (da Vinci robot) to perform surgery on the larynx (voice box) and pharynx (throat) for treatment of cancer and sleep apnea.  He is also the first Otolaryngologist in Michigan to perform a robotic-assisted thyroidectomy (thyroid surgery without a neck incision).  Dr. Lin is also a Principal Investigator in the use of novel and minimally invasive surgical approaches for treatment of OSA.  He has been involved in several industry sponsored clinical trials such as the Pillar implant (Restore Medical) and hypoglossal nerve implant (Inspire Medical) to assess the effectiveness of these new surgical approaches.

Dr. Lin's basic science research, funded by the Department of Veterans Affairs and National Cancer Institute, focuses on the development of a blood test for early detection of head and neck cancer in high risk patients.  In a paper published in Cancer Epidemiology, Biomarkers, and Preventions, he showed the use of high throughput protein microarray technology for identification of promising cancer biomarkers.  A diagnostic strategy, based on analysis of the interactions of these biomarkers with patients' sera, was capable of detecting cancer with 85% accuracy.  He has been invited to give talks on this topic in national and international meetings including the NIH's Early Detection Research Network meetings in Washington DC and Seattle.  He is currently working in collaboration with investigators from Johns Hopkins and University of Pittsburgh to further validate this diagnostic strategy.

In addition to his involvement in the residency program, Dr. Lin is also involved in both head and neck as well as sleep fellowship programs at WSU.  Dr. Lin has published extensively with over 60 publications in peer reviewed journals.  He has served on the editorial board of several journals including Laryngoscope, World Journal of Clinical Oncology, Journal of Otology & Rhinology, Otolaryngology-Head and Neck Surgery, Journal of Tumor, and Case Reports in Otolaryngology.  He also served as an ad hoc reviewer for many other journals including Cancer Biomarkers, Head and Neck, Archives of Otolaryngology-Head and Neck Surgery, World Journal of Surgical Oncology, and Journal of Clinical Oncology. 

Dr. Lin is a diplomat of the American Board of Otolaryngology-Head and Neck Surgery and is an active member of many professional societies including Southwest Oncology Group (SWOG), American Academy of Otolaryngology-Head and Neck Surgery, Triological Society, American Sleep Association, American College of Surgeons, Society of Robotic Surgery, International Surgical Sleep Society, American Academy of Sleep Medicine, and American Head & Neck Society.  He is active in many committees including the Sleep Disorder Committee and Endocrine Surgery Committee of the American Academy of Otolaryngology and the Section of Sleep Related Breathing Disorders of the American Academy of Sleep Medicine.   He currently has active staff privileges at Karmanos Cancer Institute, Harper University Hospital, Detroit Receiving Hospital, Oakwood Hospital, and John D. Dingell VA Medical Center.  He has been named Best Doctor in America (Best Doctors Inc.) and Top Doctor (Castle Connolly) for several years.  Most recently, he was named the Top Doctor on the US News and World Report.

 

Graduate degree:  M.D., Yale University School of Medicine, New Haven, CT, 1994

Residency: General Surgery, New York Hospital-Cornell Medical Center, New York, NY, 1994-1996

Otolaryngology-Head and Neck Surgery, Manhattan Eye, Ear, and Throat Hospital, New York, NY, 1996-1999

Otolaryngology-Head and Neck Surgery, New York University, New York,  NY, 1999-2000

Advanced Head and Neck Oncologic Surgery, Stanford University Medical Center, Stanford, CA, 2000-2002

 

Other Information

 GRANTS   (last 5 years)

09/18-09/22  Clinical Trial of Etanercept (TNF-a Blocker) for Treatmentof Blast-Induced Tinnitus 
                      Funding Source:  Department of Defense 
                      Site PI:  Ho-Sheng Lin
                      Main PI: Jinsheng Zhang 
                      Amount: $355,434 
                      Status: Active

09/14-08/15: Identification of Early Marker for Head and Neck Cancer through Antibody Profiling
                     Funding Source: Office of the Vice President for Research, Bridge Funding
                     PI: Ho-Sheng Lin
                     Amount: $35,000
                     Status: Closed


09/13-08/14: Identification of Early Marker for Head and Neck Cancer through Antibody Profiling 
                     Funding Source: Office of the Vice President for Research, Bridge Funding
                     PI: Ho-Sheng Lin
                     Role: PI
                     Amount: $35,000
                     Status: Closed

 

Areas of Interest

CLINICAL INTERESTS:

• Mouth Cancer
• Throat Cancer
• Neck Cancer
• Thyroid and parathyroid disease and cancer
• Parotid and submandibular gland disease and cancer
• Obstructive sleep apnea
• Snoring
• Minimally invasive surgery including TORS (transoral robotic surgery) of pharynx and larynx for cancer and sleep apnea
• Robotic assisted thyroidectomy to avoid neck incision

RESEARCH INTERESTS

• Molecular markers for diagnosis and treatment of head and neck Cancer

Publications

(last five years)

Cramer JD, Dundar Y, Hotaling J, Raza SN, Lin S. "Development and Assessment of a Novel Composite Pathologic Risk Stratification for Surgically Resected Human Papillomavirus–Associated Oropharyngeal Cancer." April 2019. JAMA Otolaryngology- Head and Neck Surgery. DOI: 10.1001/jamaoto.2019.0820  May 2019, PMID: 31042786

Dundar Y, Mandle Q, Raza SN, Lin H, Cramer JD, Hotaling JM. "Submandibular Gland Invasion by Oral Cavity Cancers: A Systematic  Review."  Otolaryngology Head and Neck Surgery. March 2019. DOI:10.1177/0194599819838475.  August, 2019, PMID: 30912983

Nguyen BK, Blasco M*, Svider PF, Lin H, Liu JK, Eloy JA, Folbe A. "Recurrence of Ventral Skull Base Lesions Attributed to Tumor Seeding: A Systematic Review." World Neurosurgery, December 2018. DOI: 10.1016/j.wneu.2018.12.104

Katherine K. Green, MD, MS; David T. Kent, MD; Mark A. D’ Agostino, MD; Paul T. Hoff, MS, MD; Ho-Sheng Lin, MD; Ryan J. Soose, MD; M. Boyd Gillespie, MD, MSc; Kathleen L. Yaremchuk, MD ; Marina Carrasco-Llatas, Md PhD ; B. Tucker Woodson, MD ; Ofer Jacobowitz, MD, PhD; Erica R. Thaler, MD; José E. Barrera, MD; Robson Capasso, MD; Stanley Yung Liu, MD, DDS; Jennifer Hsia, MD; Daljit Mann, MD; Taha S. Meraj*, MD; Jonathan A. Waxman*, MD, PhD; Eric J. Kezirian, MD, MPH "Drug-induced sleep endoscopy and surgical outcomes: a multicenter cohort study" Laryngoscope. 2018 Dec 27. doi: 10.1002/lary.27655. [Epub ahead of print]

Lin H  "Negative Pressure Wound Therapy in Head and Neck: An Evidence-Based Approach." Laryngoscope. 2019 Mar;129(3):671-683. doi: 10.1002/lary.27262. Epub 2018 Aug 22.

Tucker Woodson, Kingman P. Strohl, Ryan J. Soose, M. Boyd Gillespie, Joachim T. Maurer, Nico de Vries, Tapan A. Padhya, M. Safwan Badr, Ho-sheng Lin, Olivier M. Vanderveken, Sam Mickelson, Patrick J. Strollo Jr. "Upper Airway Stimulation for Obstructive Sleep Apnea: 5-Year Outcomes" Otolaryngol Head Neck Surg. 2018 Mar 1:194599818762383. doi: 10.1177/0194599818762383.

Ramsey T, Guo E, Svider PF*, Lin H, Syeda S, Raza SN, Fribley AM. Laryngeal Cancer: Global Socioeconomic Trends in Disease Burden and Smoking Habits.  Laryngoscope  2018 Sep;128(9):2039-2053. doi: 10.1002/lary.27068. Epub 2018 Mar 6

Soose RJ, Padhya T, Gillespie M, Froymovich O, Lin H, Woodson T. OSA Treatment History in an Upper Airway Stimulation Trial Cohort.
World J Otorhinolaryngology-Head and Neck Surgery. 2017 Jun 23;3(2):79-84. doi: 10.1016/j.wjorl.2017.05.001. eCollection 2017 Jun.

Lin HC, Weaver EM, Lin HS, Friedman M. "Multilevel Obstructive Sleep Apnea Surgery." Adv Otorhinolaryngol. 2017;80:109-115. doi: 10.1159/000470879. Epub 2017 Jul 17.

Mohamad El-Chami, Sukhesh Sudan, Ho-Sheng Lin, and Jason Mateika.  Exposure to intermittent hypoxia and sustained hypercapnia reduces therapeutic CPAP in participants with obstructive sleep apnea. J Appl Physiol. 2017 Oct 1;123(4):993-1002. doi: 10.1152/japplphysiol.00204. 2017. Epub 2017 Jul 6.

M. Boyd Gillespie, Ryan J. Soose, B. Tucker Woodson, Kingman P. Strohl, Joachim T. Maurer, Nico de Vries, David L. Steward, Jonathan Z. Baskin, M. Safwan Badr, Ho-sheng Lin, Tapan A. Padhya, Sam Mickelson, W. McDowell Anderson, Olivier M. Vanderveken, Patrick J. Strollo, on Behalf of STAR Trial Investigators.   Upper Airway Stimulation for Obstructive Sleep Apnea: Patient Reported Outcomes after 48 Months of Follow-up    Otolaryngol Head Neck Surg. 2017 Apr;156(4):765-771. doi: 10.1177/0194599817691491. Epub 2017 Feb 14.

Chau L, Jabara JT, Lai W, Svider PF*, Warner B, Lin HS, Raza SN, Fribley A.   Topical Agents for Oral Cancer Chemoprevention: A Systematic Review of the Literature.   Oral Oncology Oral Oncol. 2017 Apr;67:153-159. doi: 10.1016/j.oraloncology.2017.02.014. Epub 2017 Mar 2. Review.

Rayess HM*, Dezube A, Bawab I, Raza SN, Yoo GH, Lin HS, Jacobs JR.   Tumor differentiation as a prognostic factor for Major Salivary Gland Malignancies.   Otolaryngol Head Neck Surg. 2017 Apr 1:194599817700593. doi: 10.1177/0194599817700593.

Rayess HM*, Monk I, Svider PF*, Gupta A, Raza SN, Lin HS.  Thyroglossal Duct Cyst Carcinoma: A Systematic Review of Clinical Feature and Outcomes. Otolaryngol Head Neck Surg. 2017 May;156(5):794-802. doi: 10.1177/0194599817696504. Epub 2017 Mar 21

Wains S, ElChami M, Lin HS, Mateika JH.  Impact of arousal threshold and respiratory effort on the duration of breathing events across sleep stage and time of night.  Respiratory Physiology & Neurobiology, 2016 Dec 28;237:35-41.

Nagasaka M, Kim H, Raza SN, Yoo G, Lin HS, Sukari A.  PD1/PD-L1 Inhibitor a potential Radiosensitizer in head and neck squamous cell carcinoma: a case report.  J Immunother Cancer. 2016 Nov 15;4:83.

Hanba C*, Bobian M*, Svider PF*, Sheyn A, Siegel B, Lin HS, Raza SN.  Perioperative Considerations and Complications in Pediatric Parathyroidectomy.  Int J Pediatr Otorhinolaryngol. 2016 Dec;91:94-99. doi: 10.1016/j.ijporl.2016.10.017.

Svider PF*, Blasco M*, Raza SN, Shkoukani M, Sukari A, Yoo G, Folbe AJ, Lin HS, Fribley A.  Head and Neck Cancer: Underfunded, Understudied, Underappreciated?  Otolaryngol Head Neck Surg., 2017 Jan;156(1):10-13.

Lin HS, Terris DJ.  An Update on the status of nerve monitoring for thyroid/parathyroid surgery.  Curr Opin Oncol. 2017 Jan;29(1):14-19.

Curtis Hanba*, Peter F. Svider*, Bianca Siegel, Tony Sheyn, Mahdi Shkoukani, Ho-Sheng Lin, S. Naweed Raza.   Pediatric Thyroidectomy: Hospital Course and Perioperative Complications.  Otolaryngol Head Neck Surg. 2017 Feb;156(2):360-367. doi: 10.1177/0194599816677527. Epub 2016 Dec 20

Chopra S, Kamdar D, Cohen D, Heilbrun L, Smith D, Kim H, Lin HS, Jacobs J, Yoo G.  Outcomes of nonsurgical management of locally advanced carcinomas of the sinonasal cavity.   Laryngoscope. 2016 Nov 15. doi: 10.1002/lary.26228. [Epub ahead of print]

Ikuko Kato, Adrian Vasquez, Gregory Moyerbrailean, Susan Land, Jun Sun, Ho-Sheng Lin, Jeffrey L. Ram.  Nutritional Correlates of Human Oral Microbiome.   J Am Coll Nutr. 2016 Oct 31:1-11. [Epub ahead of print]

Ikuko Kato, Adrian Vasquez, Gregory Moyerbrailean, Susan Land, Jun Sun, Ho-Sheng Lin, Jeffrey L. Ram.  Oral Microbiome and History of Smoking and Colorectal Cancer.  Journal of Epidemiological Research, 2016, Vol. 2, No. 2, p92-101.

Cohen DS*, Low GMI, Melkane AE, Mutchnick SA*, Waxman JA*, Patel S, Shkoukani MA, Lin HS.  Establishing a Danger Zone: An anatomic study of the lingual artery in base of tongue surgery.  Laryngoscope. 2016 May 30. doi: 10.1002/lary.26048. [Epub ahead of print]

Hurst NJ Jr, Pereira LM, Dominello MM, Dyson G, Laszewski P, Robinette R, Lin HS, Yoo G, Sukari A, Kim H.  Pretreatment Computed Tomographic Gross Tumor Volume as Predictive of Persistence of Tracheostomy and Percutaneous Endoscopic Gastrostomy Tube in Patients Undergoing Larynx Preservation.  Head Neck. 2016 Oct;38(10):1455-8. doi: 10.1002/hed.24458. Epub 2016 Apr 30.

Svider PF*, Bobian M*, Lin HS, Setzen M, Baredes S, Eloy JA, Folbe AJ.  Are Industry Financial Ties Associated with Greater Scholarly Impact Among Academic Otolaryngologists?  Laryngoscope. 2016 Apr 26. doi: 10.1002/lary.26027. [Epub ahead of print]

Houmehr Hojjat*, Peter F. Svider*, Ho-Sheng Lin, Adam J. Folbe, Mahdi A. Shkoukani, Jean Anderson Eloy, Giancarlo Zuliani.  Adding Injury to Insult: A Population-Based Analysis of Combat-Sport Related Facial Injury.  Ann Otol Rhinol Laryngol. 2016 Aug;125(8):652-9. doi: 10.1177/0003489416644617. Epub 2016 May 17.

Bhat ZY, Cadnapaphornchai P, Ginsburg K, Sivagnanam M, Chopra S, Treadway CK, Lin HS, Yoo G, Sukari A, Doshi MD.  Understanding the Risk Factors and Long-Term Consequences of Cisplatin-Associated Acute Kidney Injury: An Observational Cohort Study.  PLoS One. 2015 Nov 10;10(11):e0142225. doi: 10.1371/journal.pone.0142225. eCollection 2015.

B. Tucker Woodson, Ryan J. Soose, M. Boyd Gillespie, Kingman P. Strohl, Joachim T. Maurer, Nico de Vries, David L. Steward, Jonathan Z. Baskin, Tapan A. Padhya, W. McDowell Anderson, M. Safwan Badr, Ho-Sheng Lin, Olivier M Vanderveken, Sam Mickelson, Patrick J. Strollo, Jr., On Behalf of STAR Trial Investigators*   Three Year Outcomes of Cranial Nerve Stimulation for Obstructive Sleep Apnea: The STAR TRIAL.
Otolaryngol Head Neck Surg. 2016 Jan;154(1):181-8. doi: 10.1177/0194599815616618.

Sidhu A, Miller J, Tripathi A, Garshott D, Brownell A, Chiego D, Arevang CJ, Zeng Q, Jackson L, Bechler S, Callaghan M, Yoo G, Sethi S, Lin HS, Callaghan J, Tamayo-Castillo G, Sherman D, Kaufman R, Fribley A.   Borrelidin induces the unfolded protein response in oral cancer cells and chop-dependent apoptosis.  ACS Med Chem Lett. 2015 Sep 8;6(11):1122-7. doi: 10.1021/acsmedchemlett.5b00133. eCollection 2015 Nov 12.

Shaigany K, Abrol A, Svider PF*, Eloy JA, Carron MA, Lin HS, Folbe AJ.   Recreational Motor Vehicle Use and Facial Trauma.  Laryngoscope. 2016 Jan;126(1):67-72. doi: 10.1002/lary.25557. Epub 2015 Oct 12.

ElChami M, Shaheen D, Ivers B, Syed Z, Badr MS, Lin HS, Mateika JH. Time of day affects the frequency and duration of breathing events and the critical closing pressure during NREM sleep in participants with sleep apnea.  J Appl Physiol (1985). 2015 Sep 15;119(6):617-26. doi: 10.1152/japplphysiol.00346.2015. Epub 2015 Jul 16.

Ryan J. Soose, Eileen Chasens, B. Tucker Woodson, M. Boyd Gillespie, Joachim T. Maurer, Nico de Vries, David L. Steward, Jonathan Z. Baskin, Tapan A. Padhya, Ho-sheng Lin, Sam Mickelson, Olivier M Vanderveken, Safwan M. Badr, Kingman P. Strohl, Patrick J. Strollo, Jr.,
On Behalf of STAR Trial Investigators*.   Upper Airway Stimulation for Obstructive Sleep Apnea: Self-reported Outcomes at 24 Months
J Clin Sleep Med. 2016 Jan;12(1):43-8. doi: 10.5664/jcsm.5390.

Dubal DM, Svider PS*, Folbe AJ, Lin H, Park RC, Baredes S, Eloy JA.  Laryngeal Adenoid Cystic Carcinoma: A Population-Based Perspective.  Laryngoscope 2015 Nov;125(11):2485-90. doi: 10.1002/lary.25448. Epub 2015 Jul 7.

Sukari A, Al-Hajeili M, Salem M, Heilbrun L, Smith D, Yoo GH, Jacobs JR, Lin HS, Kucuk O.  Biweekly Gemcitabine and Paclitaxel in Patients with Relapsed or Metastatic Squamous Cell Carcinoma of Head and Neck.  Avicenna J Med. 2015 Apr-Jun;5(2):36-41. doi: 10.4103/2231-0770.154195.

Xi Y, Garshott D, Free T, Yoo N, Callaghan M, Yoo G, Lin HS, Kaufman R, Fribley A. Cantharidins induce ER stress and a terminal unfolded protein response in OSCC (JDR-14-0354)  J Dent Res. 2015 Feb;94(2):320-9. doi: 10.1177/0022034514559376. Epub 2014 Nov 25.

Dowdall JR, Zak IT, Hamdan MA, Lin HS, Carron MA. (2014) Neurofibromatosis Type-2 Presenting as a Giant Neck Mass and Hearing Loss.  J Otol Rhinol 3:2. doi:10.4172/2324-8785.1000148

Lin HS, Rowley JA, Folbe A, Yoo GH, Badr MS, Chen W. Transoral Robotic Surgery for Treatment of Obstructive Sleep Apnea: Factors Predicting Surgical Response. Laryngoscope. 2015 Apr;125(4):1013-20. doi: 10.1002/lary.24970. Epub 2014 Oct 24.

Boppana NB, Kodiha M, Stochaj U, Lin HS, Haimovitz-Friedman A, Bielawska A, Bielawski J, Divine GW, Boyd JA, Korbelik M, Separovic D. Ceramide synthase inhibitor fumonisin 1 inhibits apoptotic cell death in SCC17B human head and neck squamous carcinoma cells after Pc4 photosensitization. Photochem Photobiol Sci. 2014 Nov;13(11):1621-7. doi: 10.1039/c4pp00292j.

Lauren A. Lawrence, Jose L. Jiron, Jr., Ho-Sheng Lin, Adam J. Folbe. Levamisole-Adulterated Cocaine Induced Skin Necrosis of Nose, Ears, and Extremities: Case Report. Allergy Rhinol (Providence). 2014 Jan;5(3):132-6. doi: 10.2500/ar.2014.5.0101.

ElChami M, Shaheen D, Ivers B, Syed Z, Badr MS, Lin HS, Mateika JH. Time of day affects chemoreflex sensitivity and the carbon dioxide reserve during NREM sleep in participants with sleep apnea. J Appl Physiol (1985). 2014 Nov 15;117(10):1149-56. doi: 10.1152/japplphysiol.00681.2014. Epub 2014 Sep 11.

Woodson BT, Gillespie MB, Soose R, Mauer J, deVries N, David Steward, Baskin JZ, Padhya T, Lin HS, Mickelson S, Badr SM, Strohl K, Strollo P, Jr. for the STAR Trial Group*.  Randomized Controlled Trial of Withdrawal Effect for Upper Airway (CNXII) Stimulation on Treatment of Obstructive Sleep Apnea: The STAR Trial.  Otolaryngol Head Neck Surg. 2014 Nov;151(5):880-7. doi: 10.1177/0194599814544445. Epub 2014 Sep 9.

Cohen DS, VandeGriend ZP, Yoo GH, Folbe AJ, Lin HS. Risk Stratification Based on Thyroid Cytology: Can We Rely on National Data? Am J Otolaryngol. 2014 May-Jun;35(3):362-5. doi: 10.1016/j.amjoto.2013.12.014. Epub 2014 Jan 2. 

Folbe AJ, Svider PF*, Setzen M, Zuliani G, Lin HS, Eloy JA. Scientific inquiry into rhinosinusitis: who is receiving funding from the national institutes of health?  Laryngoscope. 2014 Jun;124(6):1301-7. doi: 10.1002/lary.24525. Epub 2014 Jan 8.

Lin HS, Talwar HS, Chen W, Voichita C, Smith M, Jalapalan G*, Chatterjee M, Yoo GH, Draghici S, Sethi S, Kim H, Sukari A, Siddiq F, Folbe AJ, Tainsky MA.  Serum Biomarkers of Prognosis in Head and Neck Cancer Patients  Laryngoscope. 2014 Aug;124(8):1819-26. doi: 10.1002/lary.24567. Epub 2014 Jan 29.

Mahmood G*, Patel S*, Lin HS. Traumatic Pneumonmediastinum after Emesis Two Years after Laryngeal Fracture Repair.  J Otol Rhinol 2:4. doi:10.4172/2324-8785.1000131  http://www.scitechnol.com/2324-8785/2324-8785-2-131.php?article_id=1386 


Book Authorships and Chapters

2018 Bliznikas D, Lin HS.  Chapter 13: The Impact of Surgical Treatment of OSA on Cardiac Risk Factors in Sleep Apnea and Snoring, Surgical and Non-Surgical Therapy.  Editor: Michael Friedman and Ofer Jacobowitz, Elsevier

2018 Lin H. Chapter 64. Salvage of failed palate procedures for sleep-disordered breathing, in Sleep Apnea and Snoring, Surgical and Non-Surgical Therapy.  Editor: Michael Friedman and Ofer Jacobowitz,  Elsevier

2016 Lin H. Chapter 8. Transoral Robotic Surgery as Single Level Surgery for Treatment of Obstructive Sleep Apnea;  Transoral Robotic Surgery for Obstructive Sleep Apnea: A Practical Guide to Surgical Approach and Patient Management.   Editor: Claudio Vicini, Paul T. Hoff, Filippo Montevecchi,  Springer

Lin H, Fee WE. Malignant Nasopharyngeal Tumors. Medscape Reference. Updated July 1, 2014. Available at: http://emedicine.medscape.com/article/848163-overview.

 

Research

1.  Use of new tools for evaluation of upper airway in patients with obstructive sleep apnea
2.  Use of new surgical techniques in treatment of patients with obstructive sleep apnea
3.  Use of new and minimally invasive technology such as minimally invasive thyroid surgery and robotic technology (Da Vinci robot) in head and neck surgery
4.  Molecular markers for diagnosis and treatment of head and neck Cancer

Clinical Trial Activities 

2012-present:  Phase I/II trial of Cediranib alone or Cediranib and Lenalidomide in iodine 131 refractory differentiated
thyroid cancer
Role: Co-investigator
Status: Current

2012-present:  A phase I study of the safety, pharmacokinetics and pharmacodynamics of escalating doses of the 
selective inhibitor of nuclear export (SINE) KPT-330 in patients with advanced or metastatic solid tumor malignancies
Role: Co-investigator
Status: Current    
    
2012-present: Methotrexate and Cetuximab in Local Non-Resectable or Metastatic Advanced Head and Neck Squamous Cell Carcinoma
Role: Co-investigator
Status: Current

2010-present: A Phase II of AT-101 in Combination with Docetaxel in Patients with Recurrent, Locally Advanced or Metastatic Squamous Cell Carcinoma of the Head and Neck (SCCHN)
Role: Co-investigator
Status: Current



 

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